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Don't forget to make your picks for a chance to win a trip to Hawaii in our Pro Football Picks Contest, powered by Aruba Steve's.
Chargers at Broncos (Thursday 8:25pm)
The Chargers have a knack for playing well in Denver (having won 3 of the last 4). No Wes Welker for the Broncos, but that shouldn't stop them.
Patriots at Dolphins (Sunday 1pm)
Life without Gronk (again) begins anew for New England. Will the Dolphins be the first beneficiaries?
Redskins at Falcons (Sunday 1pm)
Washington is a mess even though the fallout may be that the Skins field a better QB this week with Kirk Cousins in for RGIII.
Bears at Browns (Sunday 1pm)
Cutler or McCown. That's the question for the Bears. The question for Cleveland is how do the Browns respond to losing a 13 point lead in 63 seconds in losing at New England last Sunday.
Texans at Colts (Sunday 1pm)
The Colts are reeling. The Texans are reeling more.
Bills at Jaguars (Sunday 1pm)
The hottest team in the AFC South plays in Jacksonville. So, for the 2nd straight week, Buffalo will lose to a team that started the season 0-8.
Eagles at Vikings (Sunday 1pm)
Both Adrian Peterson and Toby Gerhart are hurt. Fantasy football players will love Nick Foles this week (again!).
Seahawks at Giants (Sunday 1pm)
Consider this the MetLife Stadium dress rehearsal for Seattle. Opening night should come February 2nd.
49ers at Bucs (Sunday 1pm)
This one will be closer than you think and could be a trap game for the Niners, coming off an emotional win over the Seahawks.
Jets at Panthers (Sunday 4pm)
Not exactly what the Doctor ordered for the Jets: a trip to Carolina to face an angry Panthers team coming off an awful night in New Orleans last Sunday.
Chiefs at Raiders (sunday 4pm)
If only the Chiefs could face RGIII every Sunday.
Packers at Cowboys (Sunday 4:25pm)
Can the Cowboys "D" look any worse than they did last Monday night in Chicago? Not facing Aaron Rodgers would help.
Saints at Rams (Sunday 4:25pm)
Rolling, rolling, rolling. Saints in a Dome keep rolling.
Cardinals at Titans (Sunday 4:25pm)
Must win spot for Arizona here to keep pace in the NFC Playoff Chase.
Bengals at Steelers (Sunday 8:30pm)
If the Bengals are to be real players in the AFC, games like this, on the road against an inferior team, are must wins. Do you trust the Bengals?
Ravens at Lions (Monday 8:40pm)
We keep saying it, the Lions just can't stand prosperity. Home loss here against a team that knows how to win in December would be devastating to the playoff cause.
Last week: 14-2